Anti-inflammatory medications - salicylates

Depletions

Iron

Your body need iron for red blood cells to carry oxygen to all your organs and tissues. Taking aspirin or other drugs like aspirin for a long time may cause stomach bleeding, which can lead to low iron levels. Low levels of iron can cause anemia and a weakened immune system. Symptoms of anemia include being tired all the time, dizziness, shortness of breath, pale skin, and sometimes irregular heartbeat.

Vitamin B9 (Folic Acid)

Low levels of folic acid have been linked to anemia, heart disease, birth defects, and colon cancer. Symptoms may include fatigue, mouth sores, swollen tongue, and poor growth.

Vitamin C (Ascorbic Acid)

Low levels of vitamin C can cause your gums to bleed and your skin to bruise easily. Other symptoms include wounds that are slow to heal, dry hair, fatigue and anemia, and dry, rough skin. In severe cases, vitamin C deficiency leads to scurvy, a life-threatening condition that affects muscles and bones. Scurvy is rare, however, because it's easy to get enough vitamin C in your diet.

Zinc

Signs and symptoms of low levels of zinc include loss of appetite or sense of taste, weakened immune system, slow growth, skin changes, and being more susceptible to infection.

Supporting Research

Ames BN. Micronutrient deficiencies: A major cause of DNA damage. Ann NY Acad Sci. 2000;889:87-106.

Humphreys M. Potassium disturbances and associated electrocardiogram changes. Emerg Nurse. 2007;15(5):28-34.

Li Y, Schellhorn HE. New developments and novel therapeutic perspectives for vitamin C. J Nutr. 2007;137(10):2171-84.

Liamis G, Mitrogianni Z, Liberopoulos EN, Tsimihodimos V, Elisaf M. Electrolyte disturbances in patients with hyponatremia. Intern Med. 2007;46(11):685-90.

Lin SH, Halperin ML. Hypokalemia: a practical approach to diagnosis and its genetic basis. Curr Med Chem. 2007;14(14):1551-65.

Moretti R, Torre P, Antonello RM, Cazzato G, Cattaruzza T, Scapicchio PL. Vitamin B12 and folate depletion: clinical evidence in a neurological population. Neurologist. 2004;10(6):338-43.

Pelton R, LaValle J, Hawkins EB, et al. Drug Induced Nutrient Depletion Handbook. Hudson, OH:LexiComp, Inc. 2001:422-424.

Reynolds E. Vitamin B12, folic acid, and the nervous system. Lancet Neurol. 2006;5(11):949-60.

Thompson J. Vitamins, minerals and supplements: overview of vitamin C (5). Community Pract. 2007;80(1):35-6.

Zimmermann MB, Hurrell RF. Nutritional iron deficiency. Lancet. 2007;370(9586):511-20.

Alternative Names

Overview

Medications

  • Aspirin
    • Anacin[OTC]
    • Arthritis Foundation Pain Reliever [OTC]
    • Ascriptin[OTC]
    • Aspergum[OTC]
    • Asprimox[OTC]
    • Bayer Aspirin [OTC]
    • Bayer Buffered Aspirin [OTC]
    • Bayer Low Adult Strength [OTC]
    • BC Headache [OTC]
    • Bufferin[OTC]
    • Buffex[OTC]
    • Cama Arthritis Pain Reliever [OTC]
    • Easprin
    • Ecotrin Low Adult Strength [OTC]
    • Ecotrin[OTC]
    • Empirin[OTC]
    • Excedrin [OTC]
    • Excedrin Migraine [OTC]
    • Extra Strength Adprin-B[OTC]
    • Extra Strength Bayer Enteric 500 Aspirin [OTC]
    • Extra Strength Bayer Plus [OTC]
    • Goody's Headache Powders [OTC]
    • Halfprin® 81[OTC]
    • Heartline[OTC]
    • Regular Strength Bayer Enteric 500 Aspirin [OTC]
    • St Joseph Adult Chewable Aspirin [OTC]
    • ZORprin

Editorial Note

The information presented here covers some of the nutrients that may be lowered when you take certain medications. The signs and symptoms listed can be caused by other conditions. So if you have these signs and symptoms, it doesn't always mean you have low levels of these nutrients. Many things affect the level of nutrients, including your medical history, diet, and lifestyle, as well as how long you have been taking the medication. Please talk with your health care provider. He or she can best address your health care needs and see if you are at risk for low levels of any nutrients.

Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed HealthCare Network.
Review Date: September 29, 2012

A.D.A.M. quality A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process, and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation ( www.HONcode.ch.)

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