Alvimopan (By mouth)

Introduction

Alvimopan (al-vi-MOE-pan)

Helps restore normal bowel function in patients who have just had a bowel surgery.

Brand Name(s)

Entereg

When This Medicine Should Not Be Used

How to Use This Medicine

Capsule

• A nurse or other trained health professional will give you this medicine.
• This medicine is used only as part of a special program called Entereg® Access Support and Education (E.A.S.E.) in hospitalized patients. It is intended for short-term use only.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Tell your doctor if you have used narcotic pain relievers (such as codeine, fentanyl, methadone, morphine, Avinza®, Dolophine®, or Sublimaze®) for more than a week before you start taking this medicine.

Warnings While Using This Medicine

• Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, or blocked bowels.
• Taking this medicine for more than 15 doses may increase the risk for a heart attack. Patients should not receive more than 15 doses of this medicine.
• Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Constipation, passing gas, or upset stomach.
• Decrease in how much or how often you urinate.
• Dry mouth, increased thirst, muscle cramps, nausea, or vomiting.
• Unusual bleeding, bruising, or weakness.

If you notice these less serious side effects, talk with your doctor:

• Back pain.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088