Amlodipine/valsartan/hydrochlorothiazide (By mouth)

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

How to Use This Medicine

Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Carefully follow your doctor's instructions about any special diet.Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Brand Name(s)

Exforge HCT

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

Do not use this medicine if you have had an allergic reaction to amlodipine, valsartan, hydrochlorothiazide, or a sulfonamide (sulfa drug), or if you are pregnant. Do not use this medicine if you are not able to urinate. Do not use this medicine together with aliskiren (Tekturna®) if you have diabetes.

Warnings While Using This Medicine

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Make sure your doctor knows if you are breastfeeding or if you have kidney problems, liver disease, heart or blood vessel disease (including heart failure or a history of a heart attack), diabetes, glaucoma, gout, high cholesterol levels, gallstones, or lupus. Tell your doctor if you have a mineral imbalance (such as high or low potassium or sodium in the blood) or a history of asthma or allergies. Tell your doctor if you have had angioedema that was caused by a blood pressure medicine.
  • This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. Stand or sit up slowly if you are dizzy. This is more likely to happen when you begin to use the medicine or if you become dehydrated.
  • Call your doctor right away if you have chest pain that is worse than usual; trouble breathing; nausea or vomiting; pain or discomfort in your arms, jaw, back, or neck; fainting; or unusual sweating. This medicine may worsen the symptoms of an existing heart problem.
  • Call your doctor immediately if you have blurred vision, trouble seeing, eye pain, or any other change in vision. These could be symptoms of glaucoma, which could cause permanent damage to your vision.
  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in normal range. You may have to take blood pressure medicine for the rest of your life.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Introduction

Amlodipine Besylate (am-LOE-di-peen BES-i-late), Hydrochlorothiazide (hye-droe-klor-oh-THYE-a-zide), Valsartan (val-SAR-tan)

Treats high blood pressure. A lower blood pressure can reduce the risk of stroke and heart attack. This medicine contains a calcium channel blocker (CCB), an angiotensin receptor blocker (ARB), and a thiazide diuretic (water pill).

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using another blood pressure medicine (such as aliskiren, benazepril, enalapril, lisinopril, Avalide®, Avapro®, Benicar®, Cozaar®, Diovan®, Lotrel®, Micardis®, Tekturna®, Vasotec®, Zestoretic®, Zestril®) or a diuretic (water pill, such as amiloride, spironolactone, triamterene, Aldactone®).
  • Make sure your doctor knows if you also use cyclosporine (Gengraf®, Neoral®, Sandimmune®), digoxin (Lanoxin®), lithium (Eskalith®, Lithobid®), simvastatin (Zocor®), an NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, Voltaren®), insulin or an oral diabetes medicine (such as glimepiride, glyburide, metformin, Actos®, Janumet®, Januvia®), medicine to lower cholesterol (such as cholestyramine, colestipol, Colestid®, Questran®), or cancer medicines (such as cyclophosphamide, methotrexate, Cytoxan®, Rheumatrex®, Trexall®).
  • Tell your doctor if you are also using atropine, biperiden (Akineton®), carbamazepine (Tegretol®), medicine to treat HIV/AIDS (such as ritonavir, Norvir®), medicine to treat an infection (such as clarithromycin, itraconazole, ketoconazole, telithromycin, Nizoral®), or medicine to treat tuberculosis (such as rifampin, rifabutin, rifapentine, Mycobutin®, Priftin®, Rifadin®, Rimactane®).
  • Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine. Tell your doctor if you drink alcohol or use pain relievers or sleeping pills.
  • Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, painful urination
  • Changes in vision
  • Chest pain that spreads to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating, faintness
  • Confusion, weakness, uneven heartbeat, numbness or tingling in your hands, feet, or lips
  • Dry mouth, increased thirst, muscle cramps, nausea or vomiting, uneven heartbeat
  • Joint pain
  • Lightheadedness, dizziness, or fainting
  • Rapid weight gain, swelling in your hands, ankles, or feet

If you notice these less serious side effects, talk with your doctor:

  • Headache

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: March 4, 2014
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.
Copyright © 1984-2014 Thomson Micromedex. All rights reserved.
Thomson Adam

Popular Health Centers

Advertisement
 
 

Sign Up for Free Newsletters

View All Newsletters

Ask Your Doctor the RIGHT Questions!

Get FREE tools and tips to get
the most from your doctor visit.
Emailed right to you!

The Ask Your Doctor email series
may contain sponsored content.
18+, US residents only please.