Calcipotriene (On the skin)

Introduction

Calcipotriene (kal-si-poe-TRYE-een)

Treats plaque psoriasis in adults.

Brand Name(s)

Dovonex, Calcitrene

When This Medicine Should Not Be Used

How to Use This Medicine

Cream, Foam, Liquid, Ointment

• Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
• This medicine is for use on the skin only. Do not get it in your eyes, nose, or mouth. Do not use it on skin areas that have cuts or scrapes. If it does get on these areas, rinse it off right away.
• Wash your hands with soap and water before and after using this medicine. If the skin on your hands is being treated with the medicine, only wash the skin that is not affected.
• To use the cream or ointment: Apply a thin layer to the red, scaly patches on your skin. Rub it in gently until it disappears into the skin. Do not get any medicine on your face or in your eyes.
• To use the liquid on your scalp: First comb your dry hair to remove extra skin flakes and scales. Part your hair so you can see the patches on your scalp. Then apply the liquid only to the affected patches. Rub it in gently until it disappears into the scalp. Do not get any medicine on your forehead or in your eyes.
• To use the foam: Break the tiny plastic piece on the nozzle of the can. Shake the can before each use. Turn the can upside down and place a small amount into the palm of your hand. Apply a thin layer to the affected area of the skin. Rub it in gently until it disappears into the skin. Do not use the medicine in or near your eyes, mouth, or vagina.
• The liquid and foam are flammable. This means they could catch on fire. Do not use these medicines near heat, an open flame, or while smoking.
• This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

If a dose is missed:

• If you miss a dose or forget to use your medicine, apply it as soon as you can. If it is almost time for your next dose, wait until then to apply the medicine and skip the missed dose. Do not apply extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze.
• The scalp solution and foam are flammable. Keep them away from an open flame or heat. Do not smoke when you are applying the medicine. Do not poke holes in the foam canister or throw it into a fire, even if the canister is empty. Do not keep the foam inside a car where it could be exposed to extreme heat.
• Ask your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine container and any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
• Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Do not use cosmetics or other skin care products on the treated skin areas.

Warnings While Using This Medicine

• Make sure your doctor knows if you are pregnant or breastfeeding.
• Stop using this medicine and check with your doctor right away if you have a skin rash, burning, stinging, redness, swelling, or irritation on the skin.
• This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.
• Do not use this medicine for a skin problem that has not been checked by your doctor.
• If your symptoms do not improve or if they get worse, call your doctor.
• Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments. Blood tests may be needed to check for any unwanted effects.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Burning, redness, or peeling of the skin.
• Extreme confusion or mood swings.
• Increase in thirst or how often you urinate.
• Muscle weakness.
• Severe skin irritation or worsening of psoriasis.
• Severe stomach pain, nausea, or vomiting.
• Uneven heartbeat.

If you notice these less serious side effects, talk with your doctor:

• Constipation.
• Loss of appetite.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088