Capreomycin (Injection)

Introduction

Capreomycin (kap-ree-oh-MYE-sin)

Treats tuberculosis (TB).

Brand Name(s)

Capastat Sulfate

When This Medicine Should Not Be Used

How to Use This Medicine

Injectable

• Your doctor will prescribe your exact dose and tell you how often it should be given.
• Keep taking this medicine for as long as your doctor ordered, even if you feel better. If you stop the medicine too soon, your infection may not completely go away.
• An IM injection is a shot given in your muscle (upper arm, thigh, or buttocks).
• This medicine should be given by a nurse or other caregiver trained to give IM shots. Sometimes you, a family member, or a friend can be taught to give your medicine.

If a dose is missed:

• Give the shot as soon as possible, unless it is almost time for your next dose.
• Skip the missed dose if it is almost time for your next regular dose.
• You should not use two doses at the same time.

How to Store and Dispose of This Medicine

• If you have your treatments at home, you may need to store your medicine. The medicine is mixed with another liquid (usually sterile water or sodium chloride solution) before it is given. After the medicine is mixed, you can keep it at room temperature for 2 days or for 14 days in the refrigerator.
• Before you have your treatment, look at the medicine. If you see any solid pieces or specks in the liquid, You should not use it.
• If you have your treatments at home, you should be given a special container for the used needles and syringes. Keep it where children or pets cannot reach it.
• Keep all medicine out of the reach of children.
• Do not share your needles, syringes, or medicine with anyone else.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if you are also being given injections of amikacin (Amikin®), gentamicin, kanamycin (Kantrex®), netilmicin (Netromycin®), streptomycin, tobramycin, or vancomycin.

Warnings While Using This Medicine

• If you are pregnant or breastfeeding, talk to your doctor before you are given this medicine.
• This medicine may cause hearing loss. Your doctor may want to test your hearing before you start your treatments with capreomycin and while you are being treated.
• Capreomycin may also cause problems with your kidneys. You may need to have blood tests to make sure your kidneys are working properly before and during the time you are given this medicine.
• Before you get this medicine, make sure your doctor knows if you already have hearing problems, kidney disease, or any allergies, especially any allergic reactions to medicine.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

• Rash or hives
• Fever, chills, or sore throat
• Unusual bleeding or bruising
• Hearing loss, ringing in your ears, or dizziness
• Heavy bleeding or a lump where the shot is given
• Urinating less than one cup a day
• Trouble breathing
• Muscle weakness

If you notice these less serious side effects, talk with your doctor:

• Pain where the shot is given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088