Dexlansoprazole (By mouth)

Introduction

Dexlansoprazole (dex-lan-SOE-pra-zole)

Treats erosive esophagitis, heartburn, gastroesophageal reflux disease (GERD), and other conditions caused by too much stomach acid. This medicine is a proton pump inhibitor (PPI).

Brand Name(s)

Dexilant

How to Store and Dispose of This Medicine

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
• Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
• Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if you are using ampicillin (Principen®, Unasyn®), digoxin (Lanoxin®), ketoconazole (Nizoral®), tacrolimus (Prograf®), an iron supplement (such as ferrous sulfate, ferrous gluconate, Feosol®, Fer-In-Sol®, or Fergon®), or a blood thinner (such as warfarin, Coumadin®, Jantoven®).
• Do not use atazanavir (Reyataz®) while you are taking this medicine.
• Make sure your doctor knows if you are also using a diuretic or "water pill" (such as bumetanide, chlorothiazide, ethacrynic acid, furosemide, hydrochlorothiazide [HCTZ], indapamide, metolazone, torsemide, Bumex®, Demadex®, Diuril®, Edecrin®, Lasix®, Lozol®, or Zaroxolyn®).

Warnings While Using This Medicine

• Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver disease, bone problems (such as osteoporosis), or a history of low magnesium levels in your blood.
• This medicine may increase your risk of breaking a bone in the hip, wrist, or spine. This is more likely if you take high doses of this medicine, use it for longer than 1 year, or are older than 50 years of age.
• Check with your doctor right away if you have a seizure, fast or pounding heartbeat, muscle spasms; shaking, or dizziness. These are symptoms of low magnesium levels in your blood (hypomagnesemia). This is more likely to occur if you take this medicine for longer than 1 year, or if you also take digoxin (Lanoxin®) or a diuretic ("water pill").
• Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments. Blood tests may be needed to check for unwanted effects.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Seizure, muscle spasms, tremors, dizziness
• Fast, pounding, or uneven heartbeat

If you notice these less serious side effects, talk with your doctor:

• Diarrhea, nausea, vomiting, gas
• Stuffy or runny nose, sneezing, cough

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

When This Medicine Should Not Be Used

How to Use This Medicine

Delayed Release Capsule

• Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
• You may take this medicine with or without food.
• Swallow the delayed-release capsule whole. If you cannot swallow the capsule whole, you may open it and pour the medicine into a tablespoon of applesauce. Swallow the mixture right away. Do not chew it. Do not store the mixed medicine for later use.
• This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

If a dose is missed:

• If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.