Fexofenadine (By mouth)

How to Store and Dispose of This Medicine

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.


Fexofenadine (fex-oh-FEN-a-deen)

Treats hay fever symptoms such as sneezing, runny nose, watery eyes, and itchy throat. Also treats chronic skin hives and itching.

How to Use This Medicine

Capsule, Liquid, Tablet, Dissolving Tablet, Long Acting Tablet

  • Take your medicine as directed.
  • It is best to take the tablet with water.
  • Shake the oral liquid well before using.
  • Make sure your hands are dry before you handle the disintegrating tablet. Peel back the foil from the blister pack, then remove the tablet. Do not push the tablet through the foil. Place the tablet in your mouth. After it has melted, swallow or take a drink of water.
  • The oral disintegrating tablet should be taken on an empty stomach. Do not chew or break the tablet.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breast-feeding, or if you have kidney disease.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Do not give this medicine to your child unless your doctor tells you to.
  • The oral disintegrating tablet contains phenylalanine. Tell your doctor if you have a condition called phenylketonuria (PKU) before taking the tablet.
  • Call your doctor if your symptoms do not improve or if they get worse.

Brand Name(s)

Allegra, Allegra Allergy, Allegra ODT, Children's Allegra Allergy, Good Neighbor Pharmacy Allergy Relief, Leader Aller-Ease, Rite Aid Allergy Relief, Sunmark Fexofenadine Hydrochloride, TopCare 24-Hour Fexofenadine Hydrochloride

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to fexofenadine or to terfenadine (Seldane®).

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using erythromycin (E-Mycin®) or ketoconazole (Nizoral®).
  • Do not use other antihistamines (cold or allergy medicines) with fexofenadine without asking your doctor.
  • Do not take antacids that contain aluminum or magnesium (such as Maalox®) within 15 minutes before or after taking fexofenadine.
  • Do not eat grapefruit or drink grapefruit, orange, or apple juice while you are using this medicine.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Ear pain, swelling, or drainage.
  • Fever, chills, cough, sore throat, and body aches.

If you notice these less serious side effects, talk with your doctor:

  • Back pain.
  • Dry mouth or stuffy nose.
  • Headache or dizziness.
  • Increased pain or cramping during menstruation.
  • Muscle pain.
  • Nausea, vomiting, diarrhea, upset stomach or indigestion.
  • Pain in arms or legs.
  • Sleepiness or unusual drowsiness.
  • Unusual tiredness or weakness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Review Date: March 4, 2014
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.
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