Restrictive cardiomyopathy refers to changes in and weakening of the heart muscle, which causes the heart to fill poorly, squeeze poorly, or both.
Cardiomyopathy - restrictive; Infiltrative cardiomyopathy
Causes, incidence, and risk factors
In restrictive cardiomyopathy, the heart is of normal size or only slightly enlarged. However, it cannot relax normally during the time between heartbeats when the blood returns from the body (diastole).
Later in the disease, the heart may not pump blood strongly. The abnormal heart function can affect the lungs, liver, and other body systems. Restrictive cardiomyopathy may affect either or both ventricles. It is usually associated with a disease of the heart muscle.
Although restrictive cardiomyopathy is a rare condition, the most common causes are amyloidosis and scarring of the heart from an unknown cause (idiopathic myocardial fibrosis). It can occur after a heart transplant.
Other causes of restrictive cardiomyopathy include:
Symptoms of heart failure are most common. Usually, these symptoms develop slowly over time. However, sometimes symptoms start very suddenly and are severe.
Common symptoms are:
or shortness of breath
- At night
- Especially with activity
- When lying flat
- Fatigue, poor exercise tolerance
- Loss of appetite
- Swelling of the abdomen
- Swelling of the feet and ankles
- Uneven or rapid pulse
Other symptoms may include:
- Chest pain
- Decreased alertness or concentration
- Low urine production
- Need to urinate at night (in adults)
Signs and tests
An examination may show:
- Enlarged (distended) or bulging neck veins
- Enlarged liver
- Lung crackles and abnormal or distant heart sounds when listening to the chest with a stethoscope
- Fluid backup into the hands and feet
- Signs of heart failure
Tests for restrictive cardiomyopathy include:
- Cardiac catheterization and coronary angiography
- Chest CT scan
- Chest x-ray
- ECG (electrocardiogram)
- Echocardiogram and Doppler study
- MRI of the heart
- Nuclear heart scan (MUGA, RNV)
- Serum iron studies
- Serum or urine protein tests
When the cause of any cardiomyopathy can be found, that condition is treated.
Few treatments are known to be effective for restrictive cardiomyopathy. The main goal of treatment is to control symptoms and improve quality of life.
The following treatments may be used to control symptoms or prevent problems:
- Blood thinning medications, either aspirin or warfarin
- Chemotherapy (in some situations)
- Diuretics to remove fluid and help improve breathing
- Medications to prevent or control uneven or abnormal heart rhythms
- Steroids for some causes
A heart transplant may be considered if the heart function is very poor and the patient has severe symptoms.
People with this condition often develop heart failure that gets worse. Problems with "leaky" heart valves may also occur.
People with restrictive cardiomyopathy may be heart transplant candidates. The outlook depends on the cause of the condition, but it is usually poor. Average survival after diagnosis is 9 years.
Calling your health care provider
Call your health care provider if you have symptoms of restrictive cardiomyopathy.
Hare JM. The dilated, restrictive, and infiltrative cardiomyopathies. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 68.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. ©1997-2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
Sign Up for Free Newsletters
Ask Your Doctor the RIGHT Questions!
the most from your doctor visit.
Emailed right to you!
The Ask Your Doctor email series
may contain sponsored content.
18+, US residents only please.
Explore Original Articles About...
Get the MOST from QualityHealth
- Top Searches
- 1. Arthritis Management: Nature Heals
- 2. 5 Digestive To-Dos
- 3. Men: Should You Shave It or Leave It?
- 4. Today's Top Fitness Trends
- 5. Sugar and Osteoarthritis : The Link
- 6. Can't Afford Your Hospital Bills?
- 7. Stay Energized All Day Long
- 8. Phobias: Who Has Them and Why?
- 9. What If Your EpiPen Fails?
- 10. 5 Costly Medical Billing Mistakes
- 1. Ice Falls Can Cause Serious Injuries
- 2. Can Inactivity Act Like a Disease?
- 3. Kale Snack Recipe for Diabetics
- 4. How Running Affects Arthritis
- 5. Sugar and Your Immunity System
- 6. Do Weight Loss Supplements Work?
- 7. 5 Super Foods for Spring
- 8. The Hazards of Reusable Bags
- 9. How to Avoid Ingrown Hairs
- 10. Health Tip: Constantly Change Shoes
- 1. 4 Common Treatments for Epilepsy
- 2. What Does a Urogynecologist Do?
- 3. GERD Without Heartburn? It's Possible
- 4. Graston Technique: Can It Work on You?
- 5. Music Therapy Can Help Autism
- 6. 8 Ways to Fight MS-Related Fatigue
- 7. Can You Still Bleed After Menopause?
- 8. Be Your Own Health Care Advocate
- 9. Why Is Syphillis on the Rise?
- 10. Ideal Weight vs. Happy Weight
The material on the QualityHealth Web site is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a physician or other qualified health provider. See additional information.