Sertoli-Leydig cell tumor
Sertoli-Leydig cell tumor is a rare cancer of the ovaries. The cancer cells produce and release a male sex hormone.
This article focuses on Sertoli-Leydig cell tumors in women. For information on Sertoli-Leydig cell tumors in men, see the article on testicular cancer.
Causes, incidence, and risk factors
The Sertoli cells are normally located in the male reproductive glands (the testes). They feed sperm cells. The Leydig cells, also located in the testes, release a male sex hormone called testosterone.
These cells are also found in a woman's ovaries and may lead to cancer. A Sertoli-Leydig cell tumor is a cancer that starts in the female ovaries, usually in younger women. The cancer cells release a male sex hormone that may cause the woman to develop facial hair, a deep voice, and other male characteristics.
In men, some cancers of the testes can start in the Sertoli and Leydig cells. These are considered types of testicular cancer. For information on Sertoli-Leydig cell tumors in men, see the article on testicular cancer.
Signs and tests
Calling your health care provider
Einhorn LH. Testicular cancer. In Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 206.
Markham M. Gynecologic cancers. In Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 205.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. ©1997-2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
Exercise: Just What the Doctor Ordered?
Treat 5 Diabetes-Related Skin Problems
Organic Cosmetics: Will Your Skin Know the Difference?
Twitching in Your Sleep: Why Does It Happen?
How to Quit Smoking: 4 Tips to Live By
Sign Up for Free Newsletters
Ask Your Doctor the RIGHT Questions!
the most from your doctor visit.
Emailed right to you!
The Ask Your Doctor email series
may contain sponsored content.
18+, US residents only please.
Explore Original Articles About...
Get the MOST from QualityHealth
- Top Searches
- 1. Arthritis Management: Nature Heals
- 2. 5 Digestive To-Dos
- 3. Men: Should You Shave It or Leave It?
- 4. Today's Top Fitness Trends
- 5. Sugar and Osteoarthritis : The Link
- 6. Can't Afford Your Hospital Bills?
- 7. Stay Energized All Day Long
- 8. Phobias: Who Has Them and Why?
- 9. What If Your EpiPen Fails?
- 10. 5 Costly Medical Billing Mistakes
- 1. Ice Falls Can Cause Serious Injuries
- 2. Can Inactivity Act Like a Disease?
- 3. Kale Snack Recipe for Diabetics
- 4. How Running Affects Arthritis
- 5. Sugar and Your Immunity System
- 6. Do Weight Loss Supplements Work?
- 7. 5 Super Foods for Spring
- 8. The Hazards of Reusable Bags
- 9. How to Avoid Ingrown Hairs
- 10. Health Tip: Constantly Change Shoes
- 1. 4 Common Treatments for Epilepsy
- 2. What Does a Urogynecologist Do?
- 3. GERD Without Heartburn? It's Possible
- 4. Graston Technique: Can It Work on You?
- 5. Music Therapy Can Help Autism
- 6. 8 Ways to Fight MS-Related Fatigue
- 7. Can You Still Bleed After Menopause?
- 8. Be Your Own Health Care Advocate
- 9. Why Is Syphillis on the Rise?
- 10. Ideal Weight vs. Happy Weight
The material on the QualityHealth Web site is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a physician or other qualified health provider. See additional information.