Definition

A nasal mucosal biopsy is surgery in which a small piece of tissue is removed from the lining of the nose and checked for disease.

Alternative Names

Biopsy - nasal mucosa; Nose biopsy

How the test is performed

A pain-killer is sprayed into the nose. In some cases, a numbing shot may be used. A small piece of the tissue that appears abnormal is removed and checked for problems in the laboratory.

How to prepare for the test

No special preparation is necessary. You may be asked to fast for a few hours before the biopsy.

How the test will feel

There may feelings of pressure or tugging during removal of the tissue. After the numbness wears off, the area may be sore for a few days. If there is bleeding, cautery (sealing of blood vessels with electric current or laser) may be needed.

Why the test is performed

Nasal mucosal biopsy is usually done when abnormal tissue is seen during examination of the nose. It may also be done when problems affecting the mucosal tissue of the nose are suspected.

Normal Values

There is normal mucosal tissue, with no abnormal growths or tissues.

What abnormal results mean

• Necrotizing granuloma (granular tumor)
• Wegener's disease
• Nasal polyps
• Nasal tumors
• Sarcoid
• Infections (tuberculosis, fungal)

What the risks are

• Infection
• Bleeding from the biopsy site

Special considerations

Avoid blowing your nose after the biopsy.

Images

Nasal mucosal biopsynasal-mucosal-biopsy003848Encyclopedia1Test

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